HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Pyrrolidine → 2-Pyrrolidin-1-yl-5-sulfamoyl-benzoic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Pyrrolidine | HCID 31268 | — |
| Edukt | 2-Chloro-5-aminosulfonylbenzoic acid | HCID 66794 | — |
| Edukt | 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid | HCID 59793489 | — |
| Produkt | 2-Pyrrolidin-1-yl-5-sulfamoyl-benzoic acid | HCID 43217634 | 19% |
Reaktionsschritte
The title compound was synthesised according to the procedure described for the synthesis of 5-Methanesulfonyl-2-pyrrolidin-1-yl-benzoic acid (Example S) from 2-Chloro-5-sulfamoyl-benzoic acid (CAS: 97-04-1; Basu; D.-G.; J.Indian Chem.Soc.; 16; 1939; 100, 106) and pyrrolidine and obtained in 19% yield. MS (m/e): 269.4 (MH− 100%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07427612B2 |
| Quelldatensatz | uspto-grants-2008_09 |
| ORD ID | ord-d2289d57af69413cb37991f35c163259 |
| Quellennotiz | uspto-grants-2008_09 |