HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodopropane → 5-(allyl-amino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | 5-Amino-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one | HCID 15937766 | — |
| Reactant | 6-Bromo-1,2,3,4-tetrahydro-8-nitro-3-quinolinamine dihydrochloride | HCID 19919357 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 5-(allyl-amino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one | HCID 15745005 | — |
| Product | 5-Diallylamino-5,6-dihydro-1H,4H-imidazo[4,5,1-ij]quinolin-2-one | HCID 15745006 | — |
Reaction Steps
Following the procedure of Example 54, but substituting allyl bromide for iodopropane and 5-(amino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one for 6-bromo-1,2,3,4-tetrahydro-8-nitro-3-quinolinamine dihydrochloride there were obtained 5-(diallylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one, mp 150-152 from ethyl acetate and 5-(allylamino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one. The latter compound was converted to the hydrochloride salt, mp 260° from methanol:ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273975 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-252df3ad80a2416db7fa9ba61eda48f4 |
| Source note | uspto-grants-1993_12 |