Acetic Anhydride → HCID 21694589, compound

HRID 327488Notes

Reaction equation

HRID 327488 reaction equation
[NH2:1][CH2:2][C:3]1[O:7][N:6]=[C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[CH:4]=1.[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[C:13]([NH:1][CH2:2][C:3]1[O:7][N:6]=[C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])[CH:4]=1)(=[O:15])[CH3:14]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 19108613HCID 19108613, compound

Product 1

HCID 21694589HCID 21694589, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

7 g (0.04313 mol) of the product from Example 12 are suspended in a solution of 70 ml of acetic anhydride in 140 ml of pyridine with intensive stirring, the starting material slowly going into solution. After completion of the reaction (TLC checking), the mixture is concentrated in vacuo and the product is crystallized from acetone. Yield: 5.5 g; melting point: 134° C.

Workup

  1. customAfter completion of the reaction (TLC checking)
  2. concentrationthe mixture is concentrated in vacuo
  3. customthe product is crystallized from acetone

Sources & evidence

ORD record
ord-1377802636ff499ba3ec69ad86a42b5b
Source dataset
uspto-grants-1993_12
Patent number
US05273989

Reaction notes

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