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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 32750생성일: 2026년 10월 25일

1-(4-(Trifluoromethyl)phenyl)piperazine → 3,4-Difluoro-N-methyl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamide

https://huagongshe.com/reaction/32750

반응식

참여 물질

역할이름HCID투입량
반응물1-(4-(Trifluoromethyl)phenyl)piperazineHCID 121718—
반응물2,3-Difluoro-5-methylsulfamoyl-benzoic acidHCID 68839247—
생성물3,4-Difluoro-N-methyl-5-[4-(4-trifluoromethyl-phenyl)-piperazine-1-carbonyl]-benzenesulfonamideHCID 59793564—

반응 단계

The title compound was prepared in analogy to Example BO by reaction of 2,3-Difluoro-5-methylsulfamoyl-benzoic acid and 1-(4-trifluromethylphenyl)piperazine (ABCR F07741NB, [30459-17-7]) to yield the title compound as a light yellow amorpous solid. (m/e): 462.1 (M−H, 100%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07427612B2
출처 데이터셋uspto-grants-2008_09
ORD IDord-1a8bd19b82374c29b65f9fafadab84ed
출처 메모uspto-grants-2008_09