Hydantoin → HCID 15752537, compound

Participants

Reaction Conditions

Reaction Steps

5.0 g of hydantoin, 8.2 g of 2-chloromethylpyridine and 6.9 g of potassium carbonate anhydride were dissolved into 100 ml of N,N-dimethylformamide and these were stirred under room temperature for 1 hour and at 80° C. for 30 minutes. The N,N-dimethylformamide was distilled off under reduced pressure and the residue was purified by silica gel column chromatography (eluate solvent; chloroform:methanol=9:1). Thus 4.8 g of the captioned compound was thus obtained.

Provenance & Evidence