HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 3-aminopropanoate → 3-[[2-[(benzyloxy)carbonyl]ethyl]carbamoyl]-N-(t-butoxycarbonyl)-L-alanine benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 3-aminopropanoate | HCID 1116164 | — |
| Reactant | (3S)-4-(benzyloxy)-3-(((tert-butoxy)carbonyl)amino)-4-oxobutanoic acid | HCID 7017887 | — |
| Product | 3-[[2-[(benzyloxy)carbonyl]ethyl]carbamoyl]-N-(t-butoxycarbonyl)-L-alanine benzyl ester | HCID 53894863 | — |
Reaction Steps
N-(t-butoxycarbonyl)-L-aspartic acid 1-benzyl ester was coupled with β-alanine benzyl ester to give 3-[[2-[(benzyloxy)carbonyl]ethyl]carbamoyl]-N-(t-butoxycarbonyl)-L-alanine benzyl ester, m.p. 77°-78° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273982 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-3f82fb44b2a04cee9e9e89032b486ee1 |
| Source note | uspto-grants-1993_12 |