HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-((1,1-dimethylethoxy)carbonyl)-beta-alanine → N-[3-[(benzyloxy)carbonyl]-N-[N-(t-butoxycarbonyl)-beta-alanyl]-L-alanyl]-3-phenyl-L-alanine benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-((1,1-dimethylethoxy)carbonyl)-beta-alanine | HCID 76809 | — |
| Reactant | L-Asp(OBzl)-L-Phe-OBzl | HCID 10004433 | — |
| Product | N-[3-[(benzyloxy)carbonyl]-N-[N-(t-butoxycarbonyl)-beta-alanyl]-L-alanyl]-3-phenyl-L-alanine benzyl ester | HCID 10371852 | — |
Reaction Steps
N-(t-butoxycarbonyl)-β-alanine was coupled with N-[3-[(benzyloxy)-carbonyl]-L-alanyl]-3-phenyl-L-alanine benzyl ester to give N-[3-[(benzyloxy)carbonyl]-N-[N-(t-butoxycarbonyl)-β-alanyl]-L-alanyl]-3-phenyl-L-alanine benzyl ester, m.p. 124°-125° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273982 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-9971ad7a40bd45ee983506004220ecbb |
| Source note | uspto-grants-1993_12 |