Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Naphthoxyacetic acid → 1,2,3,4-tetrahydro-5-methoxy-N-[2-(2-naphthalenyloxy)ethyl]-N-propyl-2-naphthalenamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Naphthoxyacetic acid | HCID 8422 | — |
| 반응물 | Phenoxyacetic Acid | HCID 19188 | — |
| 반응물 | 2-Propylamino-5-methoxytetralin | HCID 10242548 | — |
| 생성물 | 1,2,3,4-tetrahydro-5-methoxy-N-[2-(2-naphthalenyloxy)ethyl]-N-propyl-2-naphthalenamine | HCID 19926568 | — |
반응 단계
In Example 29, phenoxyacetic acid was replaced with (2-naphthoxy)acetic acid and (-)-2-(N-n-propylamino)-5-methoxytetralin was replaced with (±)-2-(N-n-propylamino)-5-methoxytetralin. The resulting oil was subjected to flash chromatography (Silica: 8:2 pet ether/EtOAc) and the product showed characteristic peaks at: NMR (300 MHz, CDCl3) δ 7.8-6.6(m, 10H), 4.15(t, 2H), 3.8(S, 3H), 0.9(t, 3H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05274003 |
| 출처 데이터셋 | uspto-grants-1993_12 |
| ORD ID | ord-ede8cac636874c9fad7af3f0d22ad6c7 |
| 출처 메모 | uspto-grants-1993_12 |