Ethyl Acetate → HCID 19926551, compound

Participants

Reaction Steps

A racemic mixture of the product of Example 36 (66 mg, 0.180 mmol) was dissolved in THF and added dropwise to a solution of BH3 in THF (2mL) and the mixture was refluxed overnight. After workup the crude mixture was subjected to flash chromatography (Silica: EtOAc) and the product showed characteristic peaks at: NMR (300 MHz, CDCl3) δ 7.3-6.5(m, 7H), 5.4-5.0(m, 3H), 0.9(t, 3H). Anal. calc. for C22H29NO2 ·HC1: Theor. C; 71.21; H; 7.79; N, 3.61. Observed: C, 71.16, H, 7.61; N, 3.55.

Provenance & Evidence