HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine → [4-(2-Fluoro-4-trifluoromethyl-phenyl)piperazin-1-yl]-(2-iodo-5-methanesulfonyl-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Fluoro-4-(trifluoromethyl)phenyl)piperazine | HCID 46837495 | — |
| Reactant | 2-Iodo-5-methanesulfonyl-benzoic acid | HCID 57445281 | — |
| Product | [4-(2-Fluoro-4-trifluoromethyl-phenyl)piperazin-1-yl]-(2-iodo-5-methanesulfonyl-phenyl)-methanone | HCID 59793591 | — |
Reaction Steps
Example CN was prepared in analogy to Example 123 from 2-Iodo-5-methanesulfonyl-benzoic acid (example BQ) and 1-(2-Fluoro-4-trifluoromethyl-phenyl)-piperazine (example H). MS (m/e): 574.2 (M+NH4+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-6b34ea0078004e6c810dbecb95356285 |
| Source note | uspto-grants-2008_09 |