HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-(Trifluoromethyl)phenyl)piperazine → (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-(Trifluoromethyl)phenyl)piperazine | HCID 121718 | — |
| Reactant | 5-Bromo-2-morpholin-4-yl-benzoyl chloride | HCID 59793514 | — |
| Product | (5-Bromo-2-morpholin-4-yl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793730 | — |
Reaction Steps
Example CR was prepared in analogy to Example 46 from 5-Bromo-2-morpholin-4-yl-benzoyl chloride (example BI) and 1-(4-Trifluoromethyl-phenyl)-piperazine (commercial). MS (m/e): 500.1 (M+H+, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-7787ad0af505496594a0bf9c50c6ef65 |
| Source note | uspto-grants-2008_09 |