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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 327644Generated: October 29, 2026

Tetrahydrofuran → 2-Methyl-2-phenoxypropan-1-ol

https://huagongshe.com/reaction/327644

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantBorane;tetrahydrofuranHCID 2723981—
Reactant2,2-Dimethylphenoxyacetic acidHCID 67854668—
Product2-Methyl-2-phenoxypropan-1-olHCID 1835167194%

Reaction Steps

This compound was prepared in 94% yield by reduction of 2,2-dimethylphenoxyacetic acid with a 1 molar solution of borane-tetrahydrofuran in tetrahydrofuran (Aldrich Chemical Co.) using the procedure of N. M. Yoon et al, J. Org. Chem. 38, 2786 (1973).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05273993
Source datasetuspto-grants-1993_12
ORD IDord-4aad4ab63ed8414dacc7c67e299655d4
Source noteuspto-grants-1993_12