2-(Benzyloxy) ethanol → HCID 19108681, compound

HRID 327668Notes

Reaction equation

HRID 327668 reaction equation
[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[CH2:6]([O:13][CH2:14][CH2:15][OH:16])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[S:1]([O:16][CH2:15][CH2:14][O:13][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:4])(=[O:3])[NH2:2]

Participants

3

Reactant 2

HCID 121412-(Benzyloxy) ethanolHCID 24499Chlorosulfamic acid

Product 1

HCID 19108681HCID 19108681, compound

Procedure

The title compound was prepared by procedures of Example 33 from sulfamoyl chloride and 2-(benzyloxy)ethanol except the oil obtained was then further purified by high pressure chromatography as described in earlier examples using methylene chloride as eluting agent. Fractions containing the title compound were combined and the solvent was evaporated under reduced pressure to give title compound in 54% yield as light-yellow, viscous oil.

Workup

  1. customobtained
  2. customwas then further purified by high pressure chromatography
  3. washas eluting agent
  4. additionFractions containing the title compound
  5. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-303cf1288ff24593a44796ab81f9f357
Source dataset
uspto-grants-1993_12
Patent number
US05273993

Reaction notes

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