Benzyl Alcohol → 136166-81-9

HRID 327679Notes

Reaction equation

HRID 327679 reaction equation
[S:1](Cl)(=[O:4])(=[O:3])[NH2:2].[CH2:6]([OH:13])[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[S:1]([O:13][CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:4])(=[O:3])[NH2:2]

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 24499Chlorosulfamic acid

Product 1

HCID 9990000136166-81-9Yield 38%

Procedure

The title compound was prepared by the procedures of Example 33 from sulfamoyl chloride and benzyl alcohol being careful to use reduced pressure at about 35° C. to remove solvents in order to avoid violent decomposition observed in another trial at higher temperature. A white solid, mp 75°-78° C., was obtained in 38% yield.

Workup

  1. customat about 35° C.
  2. customto remove solvents in order
  3. customA white solid, mp 75°-78° C., was obtained in 38% yield

Sources & evidence

ORD record
ord-405cbe9ff87f410582b4a75278a1f5a6
Source dataset
uspto-grants-1993_12
Patent number
US05273993

Reaction notes

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