HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isobutylamine → (2-Isobutylamino-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isobutylamine | HCID 6558 | — |
| Reactant | (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 59793691 | — |
| Product | (2-Isobutylamino-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone | HCID 68839632 | 49% |
Reaction Steps
The title compound was prepared according to the procedure described for example 301 from (2-Iodo-5-methanesulfonyl-phenyl)-[4-(4-trifluoromethyl-phenyl)-piperazin-1-yl]-methanone (compound CK) and and Isobutylamine (49% yield, off white foam, MS (m/e): 484.5 (M+H, 100%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07427612B2 |
| Source dataset | uspto-grants-2008_09 |
| ORD ID | ord-27dbe2fdcfef48a5abb3fe4f0fcc50b3 |
| Source note | uspto-grants-2008_09 |