Phenylacetonitrile → HCID 10420257, compound

HRID 327716Notes

Reaction equation

HRID 327716 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]([OH:9])[CH:6]=[CH:7][CH:8]=1)#[N:2].Cl[S:11]([N:14]=C=O)(=[O:13])=[O:12].C1(CC#N)C=CC=CC=1>C1(C)C=CC=CC=1>[C:1]([C:3]1[CH:4]=[C:5]([O:9][S:11](=[O:13])(=[O:12])[NH2:14])[CH:6]=[CH:7][CH:8]=1)#[N:2]

Participants

5

Reactant 3

HCID 8794PhenylacetonitrileHCID 133943-CyanophenolHCID 70918Chlorosulfonyl isocyanate

Product 1

HCID 10420257HCID 10420257, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Using the procedure described in Example 84, the title compound was prepared in 85% yield from 10.3 g (0.086 mole) of 3-cyanophenol and 8.3 ml (0.086 mole) of chlorosulfonyl isocyanate in 75 ml of toluene as a white solid, mp 101°-104° C. (benzene-acetonitrile).

Sources & evidence

ORD record
ord-e36946fa1f0543cf9e4b31e94a0c14a7
Source dataset
uspto-grants-1993_12
Patent number
US05273993

Reaction notes

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