HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-(chloromethyl)benzene → 1-(p-Chlorobenzyl)-1-[4-(quinolin-2-ylmethoxy)phenyl]hydrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-(chloromethyl)benzene | HCID 7723 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(Quinolin-2-ylmethoxy)phenylhydrazine | HCID 15225068 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Solvent | Methanol--water (1/1) | HCID 22242641 | — |
| Product | 1-(p-Chlorobenzyl)-1-[4-(quinolin-2-ylmethoxy)phenyl]hydrazine | HCID 9908402 | — |
Reaction Steps
in said step (5) reacting the 4-(quinolin-2-ylmethoxy)phenylhydrazine product of said step (4) in H2O/methanol with p-chlorobenzyl chloride, tetrabutylammonium bromide and diisopropyl ethyl amine to yield 1-(p-chlorobenzyl)-1-[4(quinolin-2-ylmethoxy)phenyl]hydrazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05274096 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-05b8e3c24c054c268c08cb5fb7073bef |
| Source note | uspto-grants-1993_12 |