Methylhydrazine → HCID 10757767, compound

HRID 327785Notes

Reaction equation

HRID 327785 reaction equation
[CH3:1][N:2]1[C:6](=[O:7])[C:5]([CH2:8][C:9]2[CH:14]=[CH:13][C:12]([S:15][CH3:16])=[CH:11][CH:10]=2)=[C:4]([C:17]([F:20])([F:19])[F:18])[NH:3]1.[CH3:21]NN>>[CH3:21][O:7][C:6]1[N:2]([CH3:1])[N:3]=[C:4]([C:17]([F:19])([F:20])[F:18])[C:5]=1[CH2:8][C:9]1[CH:10]=[CH:11][C:12]([S:15][CH3:16])=[CH:13][CH:14]=1

Participants

3

Reactant 2

HCID 6061MethylhydrazineHCID 10518446HCID 10518446, compound

Product 1

HCID 10757767HCID 10757767, compound

Procedure

The title compound was prepared as in Example 1 from 1-methyl-4-[(4-methylthiophenyl)methyl]-3-(trifluoromethyl)-2H-pyrazol-5-one, which was also prepared as in Example 1 except that methylhydrazine was used instead of hydrazine and recrystallization from toluene-hexane mixture provided the intermediate compound as off-white crystals, mp 138°-139° C.

Workup

  1. customwas used instead of hydrazine and recrystallization from toluene-hexane mixture
  2. customprovided the intermediate compound as off-white crystals, mp 138°-139° C.

Sources & evidence

ORD record
ord-c35699401d704530a58d04022aef1ea8
Source dataset
uspto-grants-1993_12
Patent number
US05274111

Reaction notes

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