HuagongsheHuagongshe Chemistry Print Report · For research reference only
hydroxylamine-O-sulfonic acid → 1-Amino-3-benzoylpyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | hydroxylamine-O-sulfonic acid | HCID 76284 | — |
| Reactant | 3-Benzoylpyrrole | HCID 2773234 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | 1-Amino-3-benzoylpyrrole | HCID 19973156 | — |
Reaction Steps
A 3-benzoylpyrrole of the formula ##STR25## in potassium hydroxide or other suitable base is reacted with hydroxylamine-O-sulfonic acid to yield a 1-amino-3-benzoylpyrrole of the formula ##STR26## This reaction typically takes place in the presence of a suitable solvent such as dimethylformamide at a temperature of about 0° to 25° C. (or at room temperature) for 0.5 to 4 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05274116 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-5254461ba2fb43b3bbf05656f276599b |
| Source note | uspto-grants-1993_12 |