HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 6-Piperidin-1-yl-isothiazolo[5,4-d]pyrimidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | HCID 178418263 | HCID 178418263 | — |
| Product | 6-Piperidin-1-yl-isothiazolo[5,4-d]pyrimidin-3-one | HCID 23287884 | 69.6% |
Reaction Steps
Using the procedure of Example 20, 20.8 g (87.4 mmol) of 4-mercapto-2-piperidin-1-yl-pyrimidine-5-carboxylic acid amide were treated with 22.2 g (87.4 mmol) of iodine to give 14.37 g of the title compound after recrystallization from dimethylformamide, mp 268°-269° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05733921 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-a80f1938cee54d1f95b65dadd5c69df2 |
| Source note | uspto-grants-1998_03 |