3-[2-[[5-[(Methylsulfonyl)oxy]pentyl]oxy]phenyl]-2-propenoic acid methyl ester → HCID 86747452, compound

HRID 327970Notes

Reaction equation

HRID 327970 reaction equation
[CH3:1][O:2][C:3](=[O:19])/C=C/C1C=CC=CC=1OCCCCCO.COC(=O)[CH:23]=[CH:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][O:37][S:38]([CH3:41])(=[O:40])=[O:39]>>[CH3:1][O:2][C:3](=[O:19])[C:24]([C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[O:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][O:37][S:38]([CH3:41])(=[O:39])=[O:40])=[CH2:23]

Participants

3

Reactant 2

HCID 537153333-[2-[[5-[(Methylsulfonyl)oxy]pentyl]oxy]phenyl]-2-propenoic acid methyl esterHCID 67780416HCID 67780416, compound

Product 1

HCID 86747452HCID 86747452, compound

Procedure

Using the procedure of example 32, 1.09 g (4.13 mmol) of (E)-3-[2-[(5-hydroxypentyl)oxy]phenyl]-2-propenoic acid methyl ester was converted into 1.37 g (97%) of (E)-(3-[2-[[5-[(methylsulfonyl)oxy]pentyl]oxy]phenyl]-2-propenoic acid methyl ester, as a yellow oil.

Sources & evidence

ORD record
ord-526e5df08b984251b6a1aa7e28159301
Source dataset
uspto-grants-1993_12
Patent number
US05273999

Reaction notes

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