1,5-Dibromopentane → HCID 54205626, compound

HRID 327978Notes

Reaction equation

HRID 327978 reaction equation
[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][C:8](=[O:23])[C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]([CH2:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:10]=1)[CH3:2].[Br:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]Br>>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][CH2:6][CH2:7][C:8](=[O:23])[C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][Br:25])=[C:11]([CH2:16][CH2:17][C:18]([O:20][CH2:21][CH3:22])=[O:19])[CH:10]=1)[CH3:2]

Participants

3

Reactant 2

HCID 81001,5-DibromopentaneHCID 54397227HCID 54397227, compound

Product 1

HCID 54205626HCID 54205626, compoundYield 85.7%

Procedure

Starting with 0.332 g (0.99 mmol) of 3-(3-ethoxy-3-oxopropyl)-4-hydroxy-δ-oxobenzenepentanoic acid ethyl ester, and 1.16 g (5.04 mmol) of 1,5-dibromopentane, the title compound was obtained in 85.7% yield as a white solid, mp 48°-49° C., using the procedure of example 21.

Sources & evidence

ORD record
ord-81a7a8bf50eb4f72aa0119ac14d0d14b
Source dataset
uspto-grants-1993_12
Patent number
US05273999

Reaction notes

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