돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 328024생성일: 2026년 10월 25일

Methanol → 2-[(6-Methoxy-6-oxohexyl)oxy]-6-[6-[[4-oxo-8-(3-phenylpropyl)-4H-1-benzopyran-7-yl]oxy]hexyl]benzenepropanoic Acid Methyl Ester

https://huagongshe.com/reaction/328024

반응식

참여 물질

역할이름HCID투입량
반응물MethanolHCID 887—
반응물2-[6-[4-Acetyl-3-hydroxy-2-(3-phenylpropyl)phenoxy]hexyl]-6-[(6-methoxy-6-oxohexyl)oxy]benzenepropanoic acid methyl esterHCID 54313286—
생성물2-[(6-Methoxy-6-oxohexyl)oxy]-6-[6-[[4-oxo-8-(3-phenylpropyl)-4H-1-benzopyran-7-yl]oxy]hexyl]benzenepropanoic Acid Methyl EsterHCID 5386789357.4%

반응 단계

Using the procedure of example 1 with the modification that methanol was used in place of ethanol, 2-[6-[4-acetyl-3-hydroxy-2-(3-phenylpropyl)phenoxy]hexyl]-6-[(6-methoxy-6-oxohexyl)oxy]benzenepropanoic acid methyl ester from the preceding example was converted into the title compound, a pale-yellow oil purified by flash-chromatography on silica gel (eluting with 3:1 toluene-ethyl acetate), in 57.4% yield.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05273999
출처 데이터셋uspto-grants-1993_12
ORD IDord-b0ff7449adb24843a6fe794fda483e37
출처 메모uspto-grants-1993_12