HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivalic acid → 8-Methoxy-1,2-dihydro-benzo[f]chromen-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivalic acid | HCID 6417 | — |
| Reactant | 6-Methoxy-2-naphthol | HCID 288634 | — |
| Reactant | Triethyl orthoacrylate | HCID 19600934 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 8-Methoxy-1,2-dihydro-benzo[f]chromen-3-one | HCID 19921912 | 86.4% |
Reaction Steps
Starting with a solution of 6.29 g (36.1 mmol) of 6-methoxy-2-naphthalenol, 12.58 g (72.2 mmol) of triethyl orthoacrylate and 1.84 g (18.1 mmol) of trimethylacetic acid in 70 mL of toluene, the title compound (7.12 g; 86.4%) was obtained as a white solid, mp 122°-123° C., using the procedure of example 220.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05273999 |
| Source dataset | uspto-grants-1993_12 |
| ORD ID | ord-5a58971592754bae92d0a5002d494dea |
| Source note | uspto-grants-1993_12 |