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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 328040Generated: October 30, 2026

8-Methoxy-1,2-dihydro-benzo[f]chromen-3-one → 1,2-Dihydro-8-hydroxy-3H-naphtho[2,1-b]pyran-3-one

https://huagongshe.com/reaction/328040

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-Methoxy-1,2-dihydro-benzo[f]chromen-3-oneHCID 19921912—
SolventEthanol ethylacetateHCID 21584252—
Product1,2-Dihydro-8-hydroxy-3H-naphtho[2,1-b]pyran-3-oneHCID 1992195770.3%

Reaction Steps

Starting with 4.84 g (21.2 mmol) of 1,2-dihydro-8-methoxy-3H-naphtho[2,1-b]pyran-3-one from the preceding example, the title compound (3.19 g; 70.3%) was obtained as an off-white solid, mp 189°-199° C. (recrystallized from ethanol-ethyl acetate), using the procedure of example 221.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05273999
Source datasetuspto-grants-1993_12
ORD IDord-e358465b0b50437d8de964947da3f6f1
Source noteuspto-grants-1993_12