Benzylamine → HCID 53694493, compound

HRID 328091Notes

Reaction equation

C(N)C1C=CC=CC=1.C(OC([NH:19][C@H:20]([C:25]([NH:27][C@H:28]([P:30](=[O:33])([OH:32])[OH:31])[CH3:29])=[O:26])[CH2:21][CH:22]([CH3:24])[CH3:23])=O)C1C=CC=CC=1>>[NH2:19][C@H:20]([C:25]([NH:27][C@H:28]([P:30](=[O:31])([OH:33])[OH:32])[CH3:29])=[O:26])[CH2:21][CH:22]([CH3:24])[CH3:23]

Participants

Reactant 2

HCID 7504Benzylamine

HCID 53915833HCID 53915833, compound

Product 1

HCID 53694493HCID 53694493, compound

Procedure

In a manner analogous to that given in Example 1 (b), from the benzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-L-leucyl)amino]-ethylphosphonic acid there was obtained (1R)-1-(L-leucylamino)-ethylphosphonic acid of melting point 238° -240° C (decomposition); [α]D20 = - 14.2° (c = 0.5% in water).

Sources & evidence

ORD record: ord-7c37b2cf211c4587be10fa2494af54fa
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04016148

Reaction notes

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