Benzylamine → HCID 14481852, compound

HRID 328092Notes

Reaction equation

C(N)C1C=CC=CC=1.C(OC([NH:19][C@H:20]([C:24]([NH:26][C@H:27]([P:29](=[O:32])([OH:31])[OH:30])[CH3:28])=[O:25])[CH:21]([CH3:23])[CH3:22])=O)C1C=CC=CC=1>>[NH2:19][C@H:20]([C:24]([NH:26][C@H:27]([P:29](=[O:30])([OH:32])[OH:31])[CH3:28])=[O:25])[CH:21]([CH3:23])[CH3:22]

Participants

Reactant 2

HCID 7504Benzylamine

HCID 54337530HCID 54337530, compound

Product 1

HCID 14481852HCID 14481852, compound

Procedure

In a manner analogous to that given in Example 35 (b), from the benzylamine salt of (1R)-1-[(N-benzyloxycarbonyl-L-valyl)amino]-ethylphosphonic acid there was obtained (1R)-1-(L-valylamino)-ethylphosphonic acid of melting point 276°-277° C (decomposition); [α]D20 = - 9.3° (c = 0.5% in water).

Sources & evidence

ORD record: ord-4f02440238004c518368f793f18ba30b
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04016148

Reaction notes

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