Benzylamine → HCID 86734617, compound

HRID 328094Notes

Reaction equation

C(N)C1C=CC=CC=1.C(OC([NH:19][C@H:20]([C:22]([NH:24][C@H:25]([C:33]([NH:35][O:36][P:37]([CH3:40])(=[O:39])[OH:38])=[O:34])[CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[O:23])[CH3:21])=O)C1C=CC=CC=1>>[NH2:19][C@H:20]([C:22]([NH:24][C@H:25]([C:33]([NH:35][O:36][P:37]([CH3:40])(=[O:38])[OH:39])=[O:34])[CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)=[O:23])[CH3:21]

Participants

Reactant 2

HCID 7504Benzylamine

HCID 86734618HCID 86734618, compound

Product 1

HCID 86734617HCID 86734617, compound

Procedure

In a manner analogous to that given in Example 7 (b), from the benzylamine salt of [(N-benzyloxycarbonyl-L-alanyl-L-phenylalanyl)amino]-methylphosphonic acid there was obtained (L-alanyl-L-phenylalanylamino)-methylphosphonic acid of melting point 278°-280° C (decomposition); [α]D20 = +8.6° (c = 0.54% in 1-N sodium hydroxide).

Sources & evidence

ORD record: ord-323a1c96228a42f4a0b0a6ebb82610e2
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04016148

Reaction notes

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