Chloroacetone → HCID 54027783, compound

HRID 328098Notes

Reaction equation

HRID 328098 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[C:6]=2[CH:20]=1.[Cl:21][CH2:22][C:23](=O)[CH3:24]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:23]([CH3:24])[CH2:22][Cl:21])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][N:15]=3)[C:6]=2[CH:20]=1

Participants

3

Reactant 2

HCID 6571ChloroacetoneHCID 12612400HCID 12612400, compound

Product 1

HCID 54027783HCID 54027783, compound

Procedure

In the manner given in Example 1, 7-bromo-2-hydrazino-5-(2-pyridyl)-3H-1,4-benzodiazepine can be reacted with chloropropanone to give 7-bromo-2-[(2-chloro-1-methylethylidene)hydrazino]-5-(2-pyridyl)-3H-1,4-benzodiazepine.

Sources & evidence

ORD record
ord-8e56d190eec24b69a1d1b2e5fba42f91
Source dataset
uspto-grants-1977_04
Patent number
US04016165

Reaction notes

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