Thionyl Chloride → HCID 21443901, compound

Participants

Reaction Steps

9.7 g of 4-amidinophenoxyacetic acid (M.p. 324° to 326° C) were suspended in 50 ml of anhydrous benzene, 29.7 of thionyl chloride were added and the whole was heated for 1 hour on the steam bath under reflux. After the reaction mixture had cooled, the solid product was filtered off with suction. 11.4 g of 4-amidinophenoxyacetyl chloride-hydrochloride melting at 142° - 143° C (with decomposition) were obtained.

Provenance & Evidence