Water → HCID 70636775, compound

HRID 328138Notes

Reaction equation

HRID 328138 reaction equation
[N:1]([CH:4]1[CH2:22][CH2:21][N:7]2[C:8]3[CH:20]=[CH:19][CH:18]=[CH:17][C:9]=3[CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[CH:6]2[CH2:5]1)=[N+]=[N-].S(OC1CCN2C3C=CC=CC=3CC3C=CC=CC=3C2C1)(C1C=CC(C)=CC=1)(=O)=O.O>CCOCC>[NH2:1][CH:4]1[CH2:22][CH2:21][N:7]2[C:8]3[CH:20]=[CH:19][CH:18]=[CH:17][C:9]=3[CH2:10][C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[CH:6]2[CH2:5]1

Participants

5

Reactant 3

HCID 962WaterHCID 86733598HCID 86733598, compoundHCID 86734600HCID 86734600, compound

Product 1

HCID 70636775HCID 70636775, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

4 g of 2-azido-1,2,3,4,10,14b-hexahydro-pyridino[1,2-a]-dibenzo[ c,f]-azepine (axial) is added to a suspension of 3 g of LiAlH 4 in dry ether. The mixture obtained is heated for 1 hour, and after that cooled down. Then 12 ml of water are added to the mixture dropwise, whereby an inorganic precipitate is formed. The inorganic residue is removed by filtration after which the filtrate is evaporated to dryness.

Workup

  1. customThe mixture obtained
  2. temperatureis heated for 1 hour
  3. temperatureafter that cooled down
  4. customwhereby an inorganic precipitate is formed
  5. customThe inorganic residue is removed by filtration after which the filtrate
  6. customis evaporated to dryness

Sources & evidence

ORD record
ord-ad23b1d214264e468fd1b919da821be3
Source dataset
uspto-grants-1977_04
Patent number
US04016161

Reaction notes

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