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Acetic Anhydride → 17alpha-Acetoxy-3-methoxy-1,3,5(10),15-estratetraene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | 3-Methoxy-1,3,5(10),15-estratetraen-17alpha-ol | HCID 22796837 | — |
| 溶媒 | Pyridine | HCID 1049 | — |
| 生成物 | 17alpha-Acetoxy-3-methoxy-1,3,5(10),15-estratetraene | HCID 22796834 | — |
反応手順
200 mg. of 3-methoxy-1,3,5(10),15-estratetraen-17α-ol is agitated for 3 hours in 2.5 ml. of pyridine with 0.5 ml. of acetic anhydride. After the product has been worked up as described in Example 4 and purified by preparative layer chromatography (eluent: hexane/ethyl acetate = 7 : 3), 170 mg. of 17α-acetoxy-3-methoxy-1,3,5(10),15-estratetraene is isolated as an oily product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04016269 |
| 出典データセット | uspto-grants-1977_04 |
| ORD ID | ord-6a5b5773a7b942a09c345d3be209d397 |
| 出典メモ | uspto-grants-1977_04 |