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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 328219Generated: October 30, 2026

2-Chloro-5-nitrobenzaldehyde → HCID 70631679, compound

https://huagongshe.com/reaction/328219

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-nitrobenzaldehydeHCID 72933—
ReactantCarbamimidoyl-acetic acid ethyl esterHCID 4599837—
SolventEthanolHCID 702—
ProductHCID 70631679HCID 7063167948%

Reaction Steps

Upon boiling a solution of 9.3 g 3-nitro-6-chlorobenzaldehyde and 13.0 g amidinoacetic acid ethyl ester in 150 ml ethanol for two hours, 2,6-diamino-4-(3-nitro-6-chlorophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester of m.p. 130° C (ethanol) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04016277
Source datasetuspto-grants-1977_04
ORD IDord-246beb6a01404ce5ab88c7f0a1d7a217
Source noteuspto-grants-1977_04