Selenium Dioxide → 2-Fluorenonylglyoxal

Participants

Reaction Steps

The thus-isolated 2-acetylfluorenon is oxidized by selenium dioxide in dioxane medium at 98°-100° C during 22 hours to obtain 2-fluorenonyl-glyoxal isolated as semiacetal, the yield being equal to 31.2 weight percent. The thus-obtained intermediate product is subjected to treatment with sodium bisulfite in 60-percent ethanol to obtain the final product crystallizable with a molecule of water. The yield of the final product amounts to 57 weight percent when calculated for the semiacetal of 2-fluorenonyl-glyoxal and to 55 weight percent when calculated for the parent fluorene (of.Sintez organicheskikh preparatov/synthesis of organic preparations/, v.4, P.77, 1953 /in Russian/; Zhurnal organicheskoy khimii /Journal of organic chemistry/, 33, 3053, 1963 (in Russian).

Provenance & Evidence