Acetic Acid → HCID 21441259, compound

HRID 328298Notes

Reaction equation

HRID 328298 reaction equation
[Br:1][C:2]1[C:21](Br)=[CH:20][CH:19]=[C:4]2[C:5]([N:7]([C:10]3([C:16]([NH2:18])=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]3)[C:8](=[O:9])[C:3]=12)=[O:6].C(O)(=O)C.C([O-])(=O)C.[Na+].[H][H]>[Pd]>[Br:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:4]2[C:5]([N:7]([C:10]3([C:16]([NH2:18])=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]3)[C:8](=[O:9])[C:3]=12)=[O:6]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 517045Sodium AcetateHCID 21441249HCID 21441249, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 21441259HCID 21441259, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A solution of 1-(3,4-dibromophthalimido)cyclohexanecarboxamide in acetic acid containing one equivalent of sodium acetate is reduced with hydrogen in the presence of palladium on carbon to give the product 1-(3-bromophthalimido) cyclohexanecarboxamide, m.p. 199°-200° C.

Sources & evidence

ORD record
ord-8d1fa4fcfc4c49a0b10bee7d5fdb48fa
Source dataset
uspto-grants-1977_04
Patent number
US04017299

Reaction notes

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