7-chloro-2-[(1-carboxyethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine → 7-Chloro-2-[[1-(methoxycarbonyl)ethylidene]-hydrazino]-5-phenyl-3H-1,4-benzodiazepine

Participants

Reaction Steps

To a solution of 0.39 g. (0.001 mole) of 7-chloro-2-[(1-carboxyethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine is added 0.164 g. (0.0011 mole) of 3-methyl-1-p-tolyltriazene. After standing at room temperature (22°-25° C.) overnight, the solution is concentrated, then diluted with ether, filtered and evaporated to give a solid. This solid is redissolved in chloroform, diluted with ether and pentane to give .17 g. of 7-chloro-2-[[1-(merhoxycarbonyl)ethylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

Provenance & Evidence