2-Oxobutanoic Acid → HCID 54280736, compound

HRID 328389Notes

Reaction equation

HRID 328389 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1.O=[C:22]([CH2:26][CH3:27])[C:23]([OH:25])=[O:24]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:22]([C:23]([OH:25])=[O:24])[CH2:26][CH3:27])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1

Participants

3

Reactant 2

HCID 582-Oxobutanoic AcidHCID 123908747-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepine

Product 1

HCID 54280736HCID 54280736, compound

Procedure

In the manner given in Example 3, 7-chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine was stirred with α-oxobutyric acid at room temperature to give 7-chloro-2-[(1-carboxypropylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

Sources & evidence

ORD record
ord-d85016bb77af4d39a6c1ee1a9f8c2ba6
Source dataset
uspto-grants-1977_04
Patent number
US04017492

Reaction notes

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