Methyl pyruvate → HCID 53647574, compound

HRID 328397Notes

Reaction equation

HRID 328397 reaction equation
[NH:1]([C:3]1[CH2:9][N:8]=[C:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=2[Cl:16])[C:6]2[CH:17]=[CH:18][CH:19]=[CH:20][C:5]=2[N:4]=1)[NH2:2].[C:21]([O:26][CH3:27])(=[O:25])[C:22]([CH3:24])=O>>[Cl:16][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=1[C:7]1[C:6]2[CH:17]=[CH:18][CH:19]=[CH:20][C:5]=2[N:4]=[C:3]([NH:1][N:2]=[C:22]([C:21]([O:26][CH3:27])=[O:25])[CH3:24])[CH2:9][N:8]=1

Participants

3

Reactant 2

HCID 11748Methyl pyruvateHCID 12612344HCID 12612344, compound

Product 1

HCID 53647574HCID 53647574, compound

Procedure

In the manner given in Example 1, 2-hydrazino-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be stirred with methyl pyruvate at room temperature to give 5-(o-chlorophenyl)-2-[[1-(methoxycarbonyl)ethylidene]-hydrazino]-3H-1,4-benzodiazepine.

Sources & evidence

ORD record
ord-87386bcc3af64121bdcca6c898d74808
Source dataset
uspto-grants-1977_04
Patent number
US04017492

Reaction notes

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