7-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepine → HCID 54145029, compound

HRID 328407Notes

Reaction equation

HRID 328407 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][NH2:13])[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1.[O:21]1[CH2:26][CH2:25][N:24]([CH2:27][CH2:28][CH2:29][C:30](=O)[C:31]([OH:33])=[O:32])[CH2:23][CH2:22]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:30]([C:31]([OH:33])=[O:32])[CH2:29][CH2:28][CH2:27][N:24]3[CH2:23][CH2:22][O:21][CH2:26][CH2:25]3)[CH2:9][N:8]=[C:7]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[C:6]=2[CH:20]=1

Participants

3

Reactant 2

HCID 123908747-Chloro-2-hydrazinyl-5-phenyl-3H-1,4-benzodiazepineHCID 21441663HCID 21441663, compound

Product 1

HCID 54145029HCID 54145029, compound

Procedure

In the manner given in Example 13, 7-chloro-2-hydrazino-5-phenyl-3H-1,4-benzodiazepine can be stirred with 5-morpholino-2-oxopentanoic acid to give 7-chloro-2-[(1-carboxy-4-morpholinobutylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

Sources & evidence

ORD record
ord-9284a5f6563c4b3ea5f55994bdf1c259
Source dataset
uspto-grants-1977_04
Patent number
US04017492

Reaction notes

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