Diazomethane → HCID 53917179, compound

HRID 328411Notes

Reaction equation

HRID 328411 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:14]([C:21]([OH:23])=[O:22])[CH2:15][N:16]3[CH2:20][CH2:19][CH2:18][CH2:17]3)[CH2:9][N:8]=[C:7]([C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)[C:6]=2[CH:30]=1.[N+](=[CH2:33])=[N-]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:11]=[C:10]([NH:12][N:13]=[C:14]([C:21]([O:23][CH3:33])=[O:22])[CH2:15][N:16]3[CH2:20][CH2:19][CH2:18][CH2:17]3)[CH2:9][N:8]=[C:7]([C:24]3[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=3)[C:6]=2[CH:30]=1

Participants

3

Reactant 2

HCID 9550DiazomethaneHCID 54058583HCID 54058583, compound

Product 1

HCID 53917179HCID 53917179, compound

Procedure

In the manner given in Example 14, 7-chloro-2-[(1-carboxy-2-pyrrolidinoethylidene)hydrazino]-5-phenyl-3H-1,4-benzodiazepine can be treated with ethereal diazomethane to give 7-chloro-2-[[1-(methoxycarbonyl)-2-pyrrolidinoethylidene]hydrazino]-5-phenyl-3H-1,4-benzodiazepine.

Sources & evidence

ORD record
ord-9f0fa7860be143619768a99e82b74a16
Source dataset
uspto-grants-1977_04
Patent number
US04017492

Reaction notes

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