HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-5-(2-chlorophenyl)-2-hydrazinyl-3H-1,4-benzodiazepine → 7-chloro-2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-5-(2-chlorophenyl)-2-hydrazinyl-3H-1,4-benzodiazepine | HCID 12390875 | — |
| Reactant | 4-(Dimethylamino)-2-oxobutanoic acid | HCID 21441574 | — |
| Product | 7-chloro-2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine | HCID 54058667 | — |
Reaction Steps
In the manner given in Example 13, 7-chloro-2-hydrazino-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be stirred with 4-(dimethylamino)-2-oxobutanoic acid at room temperature to give 7-chloro-2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04017492 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-f9ae089abdfb40eab2dbbd7d7a2d3a2e |
| Source note | uspto-grants-1977_04 |