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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 328422Generated: October 30, 2026

Diazomethane → 7-chloro-2-[[1-(methoxycarbonyl)-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine

https://huagongshe.com/reaction/328422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiazomethaneHCID 9550—
Reactant7-chloro-2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepineHCID 54058667—
Product7-chloro-2-[[1-(methoxycarbonyl)-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepineHCID 54070602—

Reaction Steps

In the manner given in Example 14, 7-chloro-2-[[1-carboxy-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine can be treated with ethereal diazomethane to give 7-chloro-2-[[1-(methoxycarbonyl)-3-(dimethylamino)propylidene]hydrazino]-5-(o-chlorophenyl)-3H-1,4-benzodiazepine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04017492
Source datasetuspto-grants-1977_04
ORD IDord-173ce7e1a9454b11886a957def29c731
Source noteuspto-grants-1977_04