Methyl Isocyanate → HCID 54181551, compound

HRID 328468Notes

Reaction equation

HRID 328468 reaction equation
[CH3:1][N:2]([CH3:11])[C:3](=[O:10])[NH:4][C:5](=[NH:9])[S:6][CH2:7][CH3:8].[CH3:12][N:13]=[C:14]=[O:15]>C(Cl)Cl>[CH3:11][N:2]([CH3:1])[C:3]([N:4]=[C:5]([S:6][CH2:7][CH3:8])[NH:9][C:14]([NH:13][CH3:12])=[O:15])=[O:10]

Participants

4

Reactant 2

HCID 12228Methyl IsocyanateHCID 152774376HCID 152774376, compound

Product 1

HCID 54181551HCID 54181551, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 5 parts of ethyl 4,4-dimethylthioallophanimidate and 1.8 parts of methylisocyanate in 70 parts of methylene chloride was refluxed for 2 hours. After evaporation of the solvent, the residue was recrystallized from ethylacetate to give ethyl N-dimethylcarbamoyl-4-methylthioallophanimidate (a compound of formula I), m.p. 109°-111.5° C.

Workup

  1. customAfter evaporation of the solvent
  2. customthe residue was recrystallized from ethylacetate

Sources & evidence

ORD record
ord-ac1b9eda79bb4078a4b3b3572e4c2498
Source dataset
uspto-grants-1977_04
Patent number
US04017529

Reaction notes

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