Boron tribromide → HCID 18690200, compound

Participants

Reaction Steps

To a solution of 4 gms. of the product from Example 1 in dichloromethane were added two equivalents of boron tribromide. The resulting mixture was stirred for 24 hours. Analysis of the reaction mixture by TLC indicated the presence of starting material, product, and some of the monohydroxy compound. Another equivalent of boron tribromide was added, and the mixture was stirred for a total of 72 hrs. TLC indicated no starting material and only traces of the monohydroxy derivative. The product was chromatographed on silica using a mixture of 10 percent ethyl acetate and 90 percent benzene to obtain 3 gms. of the title compound, m.p. 191°-192° C.

Provenance & Evidence