HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cytidine Diphosphate → 4-hydroxy-1-beta-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cytidine Diphosphate | HCID 6132 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Product | 4-hydroxy-1-beta-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate | HCID 86734645 | — |
Reaction Steps
In the manner given in Example 2D, cytidine 5'-diphosphate was hydrogenated in dilute ammonium hydroxide in the presence of a rhodium on alumina catalyst, and the mixture separated with a Craig extractor to give 4-hydroxy-1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone uridine 5'-diphosphate and 1-β-D-ribofuranosyl-tetrahydro-2(1H)-pyrimidinone 5'-diphosphate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04017606 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-f4a534c9938a426c81e57cbe69dbea59 |
| Source note | uspto-grants-1977_04 |