Sodium borohydride → HCID 54017825, compound

HRID 328552Notes

Reaction equation

[C@@H:1]1([N:10]2[CH2:18][CH:16]([CH3:17])[C:14](=[O:15])[NH:13][C:11]2=[O:12])[O:7][C@H:6]([CH2:8][OH:9])[C@H:4]([OH:5])[C@@H:2]1[OH:3].[BH4-].[Na+]>>[CH3:17][CH:16]1[CH2:18][N:10]([C@@H:1]2[O:7][C@H:6]([CH2:8][OH:9])[C@H:4]([OH:5])[C@@H:2]2[OH:3])[C:11](=[O:12])[NH:13][CH:14]1[OH:15]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 22796914HCID 22796914, compound

Product 1

HCID 54017825HCID 54017825, compound

Procedure

In the manner given in Example 2C 1-β-D-lyxofuranosyl-dihydrothymine was reduced with sodium borohydride to give 5-methyl-4-hydroxy-1-β-D-lyxofuranosyl-tetrahydro-2(1H)-pyrimidinone.

Sources & evidence

ORD record: ord-e98956fd91c042b29508f6639d0a03ce
Source dataset: uspto-grants-1977_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04017606

Reaction notes

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