HCID 13066370, compound → HCID 54073399, compound

Participants

Reaction Steps

In the manner given in Example 2D, 1-β-D-lyxofuranosyl-5-fluorouracil, [C. N. Yung et al., J. Am. Chem. Soc. 83, 4060 (1961)] was catalytically hydrogenated in ammoniacal water in the presence of a rhodium on alumina catalyst to give 5-fluoro-4-hydroxy-1-β-D-lyxofuranosyl-tetrahydro-2(1H)-pyrimidinone and 5-fluoro-1-β-D-lyxofuranosyl-tetrahydro-2(1H)-pyrimidinone which were separated by extraction in a Craig apparatus.

Provenance & Evidence