HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 21442881, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 21442887 | HCID 21442887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 21442881 | HCID 21442881 | — |
Reaction Steps
26.6 g of 5-acetyl-7-bromo-8-hydroxyquinoline are dissolved in 200 ml of tetrahydrofurane, 11 g of triethylamine are added and 9.5 g of chloroformic acid methyl ester, diluted in 50 ml of tetrahydrofurane, are added dropwise, whilst stirring and cooling. When the exothermic reaction has ended, the triethylamine hydrochloride which has separated out is removed by filtration and the clear filtrate is evaporated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04017627 |
| Source dataset | uspto-grants-1977_04 |
| ORD ID | ord-0698c38b68b540048f9b51083a04fcae |
| Source note | uspto-grants-1977_04 |