HCID 21442780, compound → HCID 21442794, compound

Participants

Reaction Steps

3-Ethyl-5-(4-benzyl-2-morpholinylmethyl)-10,11-dihydro-5H-dibenz[b,f]azepine (0.6 g) in ethanol and conc. hydrochloric acid (1 ml) was hydrogenated over 10% palladium-on-charcoal (0.4 g) . The reaction mixture was filtered, and the filtrate was concentrated to dryness. The residue was dissolved in benzene, washed with 10% aqueous sodium hydroxide and water, dried over anhydrous sodium sulfate and evaporated to afford 3-ethyl-5-(2-morpholinylmethyl)-10,11-dihydro-5H-dibenz[b,f]azepine. M.P. 146°-150° C (oxalate).

Provenance & Evidence