Hexamethylenetetramine → HCID 21442737, compound

HRID 328614Notes

Reaction equation

HRID 328614 reaction equation
[C:1]([C:9]1[C:13]([CH3:14])=[C:12]([CH3:15])[S:11][C:10]=1[N:16]1[C:20]([CH2:21]Cl)=[N:19][C:18]([C:23]([O:25][CH2:26][CH3:27])=[O:24])=[N:17]1)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1N2CN3CN(C2)C[N:29]1C3>C(O)C>[CH3:14][C:13]1[C:9]2[C:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[N:29][CH2:21][C:20]3[N:16]([N:17]=[C:18]([C:23]([O:25][CH2:26][CH3:27])=[O:24])[N:19]=3)[C:10]=2[S:11][C:12]=1[CH3:15]

Participants

4

Reactant 2

HCID 4101HexamethylenetetramineHCID 21442744HCID 21442744, compound

Product 1

HCID 21442737HCID 21442737, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of ethyl 1-(3-benzoyl-4,5-dimethyl-2-thienyl)-5-chloromethyl-1H-1,2,4-triazole-3-carboxylate, hexamethylenetetramine and ethanol is refluxed for 4 hours in the same manner as in a) to give ethyl 7,8-dimethyl-6-phenyl-4H-thieno[3,2-f]-s-triazolo[1,5-a][1,4]diazepine-2-carboxylate as colorless plates melting at 173° to 174° C.

Workup

  1. temperatureis refluxed for 4 hours in the same manner as in a)

Sources & evidence

ORD record
ord-d12cb52ca9354a02bc72662802ff13b2
Source dataset
uspto-grants-1977_04
Patent number
US04017620

Reaction notes

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